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Editorial Board
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i
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Organizing Committee/List of Sponsors
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iv
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List of Reviewers
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viii
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Preface and acknowledgements
23 July 2007
In May 2007, the International Conference on Farm Animal Reproduction is held in the Conference Center of the ancient abbey of Rolduc located in Kerkrade in the province of Limburg, The Netherlands.
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S.J. Dieleman
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S1-S2
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| Main Program. Theme: Basic Research and Implications for the Animal as a Whole |
| Session 1: From Egg to Embryo |
| Chair: S.J. Dieleman |
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Article Title |
Author(s) |
Pages |
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Regulation of animal biotechnology: Research needs
16 June 2007
Abstract: Livestock that result from biotechnology have been a part of agricultural science for over 30 years but have not entered the market place as food or fiber. Two biotechnologies are at the for...
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C.E. Rexroad,
R.D. Green,
R.J. Wall
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S3-S8
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Equine embryology: An inventory of unanswered questions
29 May 2007
Abstract: Carl Hartman's title of 47 years ago is invoked in tribute to his first recovery of a bovine embryo 30 years before that, and his legacy of an emphasis on the value of descriptive and compar...
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K.J. Betteridge
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S9-S21
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| Session 2: Environmental Factors and Oocyte Quality |
| Chair: J.F. Hasler |
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Article Title |
Author(s) |
Pages |
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Intra-ovarian regulation of follicular development and oocyte competence in farm animals
31 May 2007
Abstract: In both mono-ovulatory species, such as cattle, and poly-ovulatory species, such as pigs, the interactions among extra-ovarian gonadotropins, metabolic hormones and intra-ovarian growth fact...
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R. Webb,
P.C. Garnsworthy,
B.K. Campbell,
M.G. Hunter
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S22-S29
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Macroenvironment effects on oocytes and embryos in swine
26 May 2007
Abstract: As in other domestic mammals, the interaction between genotype and environment in swine has profound effects on the ultimate phenotype of the individual born. Interactions within the litter ...
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G.R. Foxcroft,
M.D. Vinsky,
F. Paradis,
W.-Y. Tse,
S.C. Town,
C.T. Putman,
M.K. Dyck,
W.T. Dixon
et al.
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S30-S39
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To be or not to be—Determinants of embryonic survival following heat shock
10 May 2007
Abstract: Elevated temperature can reduce developmental competence of the preimplantation embryo. Whether an embryo survives elevated temperature depends on its genotype, stage of development, exposur...
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P.J. Hansen
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S40-S48
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Use of insulin-like growth factor-1 to improve post-transfer survival of bovine embryos produced in vitro
26 May 2007
Abstract: Use of in vitro produced embryos in commercial settings is limited by alterations in embryo function that result in reduced embryo and fetal survival and increased fetal, placental and neona...
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J. Block
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S49-S55
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Metabolomics: Approaches to assessing oocyte and embryo quality
11 May 2007
Abstract: Morphological evaluation remains the primary method of embryo assessment during IVF cycles, but its modest predictive power and inherent inter- and intra-observer variability limits its valu...
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R. Singh,
K.D. Sinclair
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S56-S62
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| Session 3: Transcriptome of the Oocyte and Competence |
| Chair: P. Mermillod |
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Article Title |
Author(s) |
Pages |
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Ribosomal RNA and nucleolar proteins from the oocyte are to some degree used for embryonic nucleolar formation in cattle and pig
28 April 2007
Abstract: The nucleolus is the site of ribosomal RNA (rRNA) and ribosome production. In the bovine primordial follicle oocyte, this organelle is inactive, but in the secondary follicle an active fibri...
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P. Maddox-Hyttel,
O. Svarcova,
J. Laurincik
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S63-S70
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In vivo and in vitro effects of FSH on oocyte maturation and developmental competence
25 June 2007
Abstract: There is increasing evidence demonstrating that oocyte quality depends on the events that occur before germinal vesicle breakdown (GVBD), suggesting that the oocyte must accumulate the appro...
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M.-A. Sirard,
S. Desrosier,
M. Assidi
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S71-S76
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Messenger RNA in oocytes and embryos in relation to embryo viability
26 May 2007
Abstract: Messenger RNA (mRNA) expression techniques have become a powerful tool to analyze the relative abundance of transcripts related to oocyte and/or embryo quality. Numerous efforts to identify ...
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C. Wrenzycki,
D. Herrmann,
H. Niemann
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S77-S83
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Isolation of genes associated with developmental competency of bovine oocytes
10 May 2007
Abstract: Eggs differ widely in their ability to develop into an embryo. To address this characteristic, the concept of developmental competency has been coined, defined as the ability or potential of...
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P.L. Pfeffer,
B. Sisco,
M. Donnison,
J. Somers,
C. Smith
et al.
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S84-S90
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Global gene expression analysis during bovine oocyte in vitro maturation
21 May 2007
Abstract: It is well known that factors such as nutrition, hormonal alterations and environmental compounds can have a profound effect on oocyte quality and subsequently embryo development. Global mRN...
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T. Fair,
F. Carter,
S. Park,
A.C.O. Evans,
P. Lonergan
et al.
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S91-S97
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| Session 4: Early Embryo Development |
| Chair: I. Donnay |
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Article Title |
Author(s) |
Pages |
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Region-specific DNA methylation in the preimplantation embryo as a target for genomic plasticity
10 May 2007
Abstract: It has been long known that the unique genetic sequence each embryo inherits is not the sole determinant of phenotype. However, only recently have epigenetic modifications to DNA been implic...
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A. Thurston,
E.S. Lucas,
C. Allegrucci,
W. Steele,
L.E. Young
et al.
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S98-S106
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Selective degradation of transcripts in mammalian oocytes and embryos
18 June 2007
Abstract: During the last decade several gene expression analysis studies have been carried out to investigate the transcriptional profile of bovine embryos in response to various culture and treatmen...
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K. Schellander,
M. Hoelker,
D. Tesfaye
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S107-S115
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Reporter genes for embryogenesis research in livestock species
22 June 2007
Abstract: Currently, our knowledge of early mammalian embryogenesis, stem cell differentiation and development is largely based on studies performed in mouse models. However, in important aspects, e.g...
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F.A. Habermann,
A. Wuensch,
F. Sinowatz,
E. Wolf
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S116-S124
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Embryology in the era of proteomics
10 May 2007
Abstract: Currently, relatively little is known regarding the protein production of mammalian embryos. Unlike the genome, the proteome itself is dynamic reflecting both internal and external environme...
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M.G. Katz-Jaffe,
D.K. Gardner
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S125-S130
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Gamete origin in relation to early embryo development
10 May 2007
Abstract: Fertilization in vivo requires a complex series of selection events to occur in order to guarantee that only the fittest gametes take part in the fusion process and give rise to a viable emb...
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A. Van Soom,
L. Vandaele,
K. Goossens,
A. de Kruif,
L. Peelman
et al.
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S131-S137
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| Session 5: Fertilization |
| Chair: N. Soede |
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Article Title |
Author(s) |
Pages |
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Role of the oviduct in sperm capacitation
25 April 2007
Abstract: Following insemination of spermatozoa pre-ovulation, the mammalian oviduct ensures, by the formation of a functional sperm reservoir (SR), that suitable (low) numbers of viable and potential...
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H. Rodriguez-Martinez
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S138-S146
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A possible role for sperm RNA in early embryo development
22 June 2007
Abstract: Recently it has been demonstrated that, along with sperm, some of its RNA can be introduced into the oocyte during fertilization, which stays stable until the activation of the embryonic gen...
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A. Boerke,
S.J. Dieleman,
B.M. Gadella
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S147-S155
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Calcium and other ion dynamics during gamete maturation and fertilization
18 June 2007
Abstract: Ion currents and cytosolic free calcium ([Ca2+]i) elevations are crucial events in triggering the complex machinery involved in both gamete maturation and fertilization. Oocyte maturation is...
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Raffaele Boni,
Roberto Gualtieri,
Riccardo Talevi,
Elisabetta Tosti
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S156-S164
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| Session 6: New Techniques to Study Competence of Oocytes and Embryos |
| Chair: M.-A. Driancourt |
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Article Title |
Author(s) |
Pages |
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Application of DNA array technology to mammalian embryos
20 June 2007
Abstract: Early embryogenesis depends on a tightly choreographed succession of gene expression patterns which define normal development. Fertilization and the first zygotic cleavage involve major chan...
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H. Niemann,
J.W. Carnwath,
W. Kues
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S165-S177
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Toward culture of single gametes: The development of microfluidic platforms for assisted reproduction
26 May 2007
Abstract: During the last few decades in vitro production of mammalian embryos and assisted reproductive technologies such as embryo transfer, cryopreservation, and cloning have been used to produce a...
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M.B. Wheeler,
E.M. Walters,
D.J. Beebe
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S178-S189
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Gamete and embryo isolation and culture with microfluidics
19 June 2007
Abstract: Assisted reproductive technologies (ARTs) encompass some of the most exciting modern scientific developments that tremendously impacts society at many levels. Since the beginning of ARTs, sc...
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G.D. Smith,
S. Takayama
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S190-S195
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| Session 7: NT and Stem Cells in Relation to Competence |
| Chair: C. Keefer |
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Article Title |
Author(s) |
Pages |
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Nuclear reprogramming and pluripotency of embryonic cells: Application to the isolation of embryonic stem cells in farm animals
09 July 2007
Abstract: Despite their biological and biotechnological interest, pluripotent embryonic stem cell lines (ES cells) have been isolated from cultured embryos only in a very limited number of mammalian s...
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J.-P. Renard,
J. Maruotti,
A. Jouneau,
X. Vignon
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S196-S205
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Porcine embryonic stem cells: Facts, challenges and hopes
20 June 2007
Abstract: Embryonic stem cells (ESCs) represent a promising tool for cell therapy, regenerative medicine and tissue repair. At the same time they constitute an invaluable model for basic investigation...
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T.A.L. Brevini,
S. Antonini,
F. Cillo,
M. Crestan,
F. Gandolfi
et al.
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S206-S213
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Somatic cell nuclear transfer: Past, present and future perspectives
09 July 2007
Abstract: It is now over a decade since the birth, in 1996, of Dolly the first animal to be produced by nuclear transfer using an adult derived somatic cell as nuclear donor. Since this time similar t...
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K.H.S. Campbell,
P. Fisher,
W.C. Chen,
I. Choi,
R.D.W. Kelly,
J-H. Lee,
J. Xhu
et al.
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S214-S231
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| Satellite Program. Theme: Implications of Basic Research for Reproduction in Cattle |
| Session 1: Environmental and Developmental Competence of Oocyte and Embryo |
| Chair: P.L.A.M. Vos |
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Article Title |
Author(s) |
Pages |
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Influence of negative energy balance on cyclicity and fertility in the high producing dairy cow
10 May 2007
Abstract: The peripartum period is of critical importance to subsequent health and fertility. Most cows enter a state of negative energy balance (NEB) associated with many metabolic changes which have...
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D.C. Wathes,
M. Fenwick,
Z. Cheng,
N. Bourne,
S. Llewellyn,
D.G. Morris,
D. Kenny,
J. Murphy,
R. Fitzpatrick
et al.
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S232-S241
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Exploitation of genetic and physiological determinants of embryonic resistance to elevated temperature to improve embryonic survival in dairy cattle during heat stress
10 May 2007
Abstract: Heat stress causes large reductions in fertility in lactating dairy cows. The magnitude and geographical extent of this problem is increasing because improvements in milk yield have made it ...
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P.J. Hansen
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S242-S249
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| Session 2: Prospects of Application of Biotechnology for Future Cattle Breeding |
| Chair: S.J. Dieleman |
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Article Title |
Author(s) |
Pages |
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From biological fundamentals to practice, and back
18 June 2007
Abstract: It has become evident that advances in farm animal reproduction have become increasingly dependent on fundamental scientific research in addition to an understanding of the physiological pro...
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M.-A. Sirard
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S250-S256
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| Session 3: Management and Genetics in Relation to Fertility |
| Chair: B. Kemp |
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Article Title |
Author(s) |
Pages |
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The role of the veterinarian in bovine fertility management on modern dairy farms
11 May 2007
Abstract: The decline in dairy herd fertility internationally has highlighted the limited impact of traditional veterinary approaches to herd fertility. The role of the veterinarian in fertility manag...
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J.F. Mee
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S257-S265
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Genetics and genomics to improve fertility in high producing dairy cows
26 May 2007
Abstract: Improving dairy cow fertility by means of genetic selection is likely to become increasingly important, since it is now well established that declining fertility cannot only be arrested by i...
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R.F. Veerkamp,
B. Beerda
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S266-S273
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Effects of dietary energy source on energy balance, metabolites and reproduction variables in dairy cows in early lactation
30 May 2007
Abstract: This paper summarizes three recent studies by the same authors with the objective to study the effect of dietary energy source on the energy balance (EB) and risk for metabolic and reproduct...
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A.T.M. van Knegsel,
H. van den Brand,
J. Dijkstra,
B. Kemp
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S274-S280
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Strategies to improve fertility of high yielding dairy farms: Management of the dry period
26 May 2007
Abstract: Reproductive performance of dairy cattle has been related to a wide variety of indicators of energy status, e.g., extent of negative energy balance, time of energy balance nadir, body weight...
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R.R. Grummer
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S281-S288
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