Theriogenology
Volume 73, Issue 3 , Pages 367-382 , February 2010

Prostaglandin-D synthetase induces transcription of the LH beta subunit in the primary culture of chicken anterior pituitary cells via the PPAR signaling pathway

  • L.-R. Chen

      Affiliations

    • Division of Physiology, Taiwan Livestock Research Institute, Council of Agriculture, Tainan, Taiwan
    • Institute of Biotechnology, National Cheng Kung University, Tainan, Taiwan
    • Institute of Biotechnology, Southern Taiwan University of Technology, Tainan, Taiwan
    • These authors contributed equally.
    • ,
  • S.-C. Lee

      Affiliations

    • Department of Surgical Sciences, Zuoying Armed Forces General Hospital, Kaohsiung, Taiwan
    • These authors contributed equally.
    • ,
  • Y.-P. Lin

      Affiliations

    • Institute of Biomedical Science, National Sun Yat-sen University, Kaohsiung, Taiwan
    • These authors contributed equally.
    • ,
  • Y.-L. Hsieh

      Affiliations

    • Institute of Biomedical Science, National Sun Yat-sen University, Kaohsiung, Taiwan
    • ,
  • Y.-L. Chen

      Affiliations

    • Institute of Biomedical Science, National Sun Yat-sen University, Kaohsiung, Taiwan
    • ,
  • J.-R. Yang

      Affiliations

    • Division of Physiology, Taiwan Livestock Research Institute, Council of Agriculture, Tainan, Taiwan
    • ,
  • J.-F. Liou

      Affiliations

    • Division of Physiology, Taiwan Livestock Research Institute, Council of Agriculture, Tainan, Taiwan
    • ,
  • C.-F. Chen

      Affiliations

    • Department of Animal Science, National Chung-Hsing University, Taichung, Taiwan
    • ,
  • Y.-P. Lee

      Affiliations

    • Department of Animal Science, National Chung-Hsing University, Taichung, Taiwan
    • ,
  • Y.-L. Shiue

      Affiliations

    • Institute of Biomedical Science, National Sun Yat-sen University, Kaohsiung, Taiwan
    • Corresponding Author InformationCorresponding author. Tel.: +886 7 5255818; fax: +886 7 5250197.

Received 14 February 2009 ,Revised 16 September 2009 ,Accepted 24 September 2009.

References 

  1. Padmanabhan V, Battaglia D, Brown MB, Karsch FJ, Lee JS, Pan W, et al. Neuroendocrine control of follicle-stimulating hormone (FSH) secretion: II. Is follistatin-induced suppression of FSH secretion mediated via changes in activin availability and does it involve changes in gonadotropin-releasing hormone secretion?. Biol Reprod. 2002;66:1395–1402
  2. Opel H, Nalbandov AV. Follicular growth and ovulation in hypophysectomized hens. Endocrinology. 1961;69:1016–1028
  3. Cunningham FJ. Ovulation in the hen: neuroendocrine control. Oxf Rev Reprod Biol. 1987;9:96–136
  4. Etches RJ, Petitte JN. Reptilian and avian follicular hierarchies: models for the study of ovarian development. J Exp Zool Suppl. 1990;4:112–122
  5. Mashaly MM, Birrenkott GP, EL-Begearmi MM, Wentworth BC. Plasma LH progesterone concentrations in the turkey hen during the ovulatory cycle. Poult Sci 1976; 55:1226–1234.
  6. Sharp PJ, Dawson A, Lea RW. Control of luteinizing hormone and prolactin secretion in birds. Comp Biochem Physiol C Pharmacol Toxicol Endocrinol. 1998;119:275–282
  7. Liu HK, Lilburn MS, Koyyeri B, Anderson JW, Bacon WL. Preovulatory surge patterns of luteinizing hormone, progesterone, and estradiol-17beta in broiler breeder hens fed ad libitum or restricted fed. Poult Sci. 2004;83:823–829
  8. Gharib SD, Wierman ME, Shupnik MA, Chin WW. Molecular biology of the pituitary gonadotropins. Endocr Rev. 1990;11:177–199
  9. Landefeld TD, Kepa J, Karsch FJ. Regulation of alpha subunit synthesis by gonadal steroid feedback in the sheep anterior pituitary. J Biol Chem. 1983;258:2390–2393
  10. Nilson JH, Nejedlik MT, Virgin JB, Crowder ME, Nett TM. Expression of alpha subunit and luteinizing hormone beta genes in the ovine anterior pituitary. Estradiol suppresses accumulation of mRNAS for both alpha subunit and luteinizing hormone beta. J Biol Chem. 1983;258:12087–12090
  11. Foster DN, Galehouse D, Giordano T, Min B, Lamb IC, Porter DA, et al. Nucleotide sequence of the cDNA encoding the common alpha subunit of the chicken pituitary glycoprotein hormones. J Mol Endocrinol. 1992;8:21–27
  12. Noce T, Ando H, Ueda T, Kubokawa K, Higashinakagawa T, Ishii S. Molecular cloning and nucleotide sequence analysis of the putative cDNA for the precursor molecule of the chicken LH-beta subunit. J Mol Endocrinol. 1989;3:129–137
  13. Yang J, Kirby JD, Scarbrough K, Okimoto R. Assignment of the chicken glycoprotein hormones, alpha polypeptide (CGA) gene to chromosome 3. Anim Genet. 2004;35:67–68
  14. Kaetzel DM, Nilson JH. Methotrexate-induced amplification of the bovine lutropin genes in Chinese hamster ovary cells. Relative concentration of the alpha and beta subunits determines the extent of heterodimer assembly. J Biol Chem. 1988;263:6344–6351
  15. Shiue YL, Chen LR, Chen CF, Chen YL, Ju JP, Chao CH, et al. Identification of transcripts related to high egg production in the chicken hypothalamus and pituitary gland. Theriogenology. 2006;66:1274–1283
  16. Chen LR, Chao CH, Chen CF, Lee YP, Chen YL, Shiue YL. Expression of 25 high egg production related transcripts that identified from hypothalamus and pituitary gland in red-feather Taiwan country chickens. Anim Reprod Sci. 2007;100:172–185
  17. Chen CF, Shiue YL, Yen CJ, Tang PC, Chang HC, Lee YP. Laying traits and underlying transcripts, expressed in the hypothalamus and pituitary gland, that were associated with egg production variability in chickens. Theriogenology. 2007;68:1305–1315
  18. Tuiskula-Haavisto M, Honkatukia M, Vilkki J, de Koning DJ, Schulman NF, Maki-Tanila A. Mapping of quantitative trait loci affecting quality and production traits in egg layers. Poult Sci. 2002;81:919–927
  19. Okuda S, Yamada T, Hamajima M, Itoh M, Katayama T, Bork P, et al. KEGG Atlas mapping for global analysis of metabolic pathways. Nucleic Acids Res. 2008;36:W423–W426
  20. Herlong JL, Scott TR. Positioning prostanoids of the D and J series in the immunopathogenic scheme. Immunol Lett. 2006;102:121–131
  21. Fitzpatrick FA, Wynalda MA. Albumin-catalyzed metabolism of prostaglandin D2. Identification of products formed in vitro. J Biol Chem. 1983;258:11713–11718
  22. Helliwell RJ, Berry EB, O’Carroll SJ, Mitchell MD. Nuclear prostaglandin receptors: role in pregnancy and parturition?. Prostaglandins Leukot Essent Fatty Acids. 2004;70:149–165
  23. Thomson AM, Meyer DJ, Hayes JD. Sequence, catalytic properties and expression of chicken glutathione-dependent prostaglandin D2 synthase, a novel class Sigma glutathione S-transferase. Biochem J. 1998;333(Pt 2):317–325
  24. Tasaka K, Miyake A, Sakumoto T, Aono T, Kurachi K. Prostaglandin D2 induces release of luteinizing hormone from the rat pituitary gland without the modulation of hypothalamic luteinizing hormone releasing hormone. J Endocrinol. 1983;99:289–292
  25. Willson TM, Brown PJ, Sternbach DD, Henke BR. The PPARs: from orphan receptors to drug discovery. J Med Chem. 2000;43:527–550
  26. Straus DS, Glass CK. Cyclopentenone prostaglandins: new insights on biological activities and cellular targets. Med Res Rev. 2001;21:185–210
  27. Michalik L, Auwerx J, Berger JP, Chatterjee VK, Glass CK, Gonzalez FJ, et al. International Union of Pharmacology. LXI. Peroxisome proliferator-activated receptors. Pharmacol Rev. 2006;58:726–741
  28. Collino M, Patel NS, Thiemermann C. PPARs as new therapeutic targets for the treatment of cerebral ischemia/reperfusion injury. Ther Adv Cardiovasc Dis. 2008;2:179–197
  29. Braissant O, Foufelle F, Scotto C, Dauca M, Wahli W. Differential expression of peroxisome proliferator-activated receptors (PPARs): tissue distribution of PPAR-alpha, -beta, and -gamma in the adult rat. Endocrinology. 1996;137:354–366
  30. Bogazzi F, Russo D, Locci MT, Chifenti B, Ultimieri F, Raggi F, et al. Peroxisome proliferator-activated receptor (PPAR)gamma is highly expressed in normal human pituitary gland. J Endocrinol Invest. 2005;28:899–904
  31. Badawi AF, Badr MZ. Chemoprevention of breast cancer by targeting cyclooxygenase-2 and peroxisome proliferator-activated receptor-gamma (Review). Int J Oncol. 2002;20:1109–1122
  32. Hirata Y, Hayashi H, Ito S, Kikawa Y, Ishibashi M, Sudo M, et al. Occurrence of 9-deoxy-delta 9,delta 12-13,14-dihydroprostaglandin D2 in human urine. J Biol Chem. 1988;263:16619–16625
  33. Shibata T, Kondo M, Osawa T, Shibata N, Kobayashi M, Uchida K. 15-Deoxy-delta 12,14-prostaglandin J2. A prostaglandin D2 metabolite generated during inflammatory processes. J Biol Chem. 2002;277:10459–10466
  34. Ward JE, Tan X. Peroxisome proliferator activated receptor ligands as regulators of airway inflammation and remodelling in chronic lung disease. PPAR Res. 2007;14983:1–12
  35. Forman BM, Chen J, Evans RM. Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors alpha and delta. Proc Natl Acad Sci U S A. 1997;94:4312–4317
  36. Ricote M, Li AC, Willson TM, Kelly CJ, Glass CK. The peroxisome proliferator-activated receptor-gamma is a negative regulator of macrophage activation. Nature. 1998;391:79–82
  37. Jiang C, Ting AT, Seed B. PPAR-gamma agonists inhibit production of monocyte inflammatory cytokines. Nature. 1998;391:82–86
  38. Rossi A, Kapahi P, Natoli G, Takahashi T, Chen Y, Karin M, et al. Anti-inflammatory cyclopentenone prostaglandins are direct inhibitors of IkappaB kinase. Nature. 2000;403:103–108
  39. Straus DS, Pascual G, Li M, Welch JS, Ricote M, Hsiang CH, et al. 15-Deoxy-delta 12,14-prostaglandin J2 inhibits multiple steps in the NF-kappa B signaling pathway. Proc Natl Acad Sci U S A. 2000;97:4844–4849
  40. Inoue H, Tanabe T, Umesono K. Feedback control of cyclooxygenase-2 expression through PPARgamma. J Biol Chem. 2000;275:28028–28032
  41. Subbaramaiah K, Lin DT, Hart JC, Dannenberg AJ. Peroxisome proliferator-activated receptor gamma ligands suppress the transcriptional activation of cyclooxygenase-2. Evidence for involvement of activator protein-1 and CREB-binding protein/p300. J Biol Chem. 2001;276:12440–12448
  42. Boyault S, Simonin MA, Bianchi A, Compe E, Liagre B, Mainard D, et al. 15-Deoxy-delta12,14-PGJ2, but not troglitazone, modulates IL-1beta effects in human chondrocytes by inhibiting NF-kappaB and AP-1 activation pathways. FEBS Lett. 2001;501:24–30
  43. Heaney AP, Fernando M, Melmed S. PPAR-gamma receptor ligands: novel therapy for pituitary adenomas. J Clin Invest. 2003;111:1381–1388
  44. Emery MN, Leontiou C, Bonner SE, Merulli C, Nanzer AM, Musat M, et al. PPAR-gamma expression in pituitary tumours and the functional activity of the glitazones: evidence that any anti-proliferative effect of the glitazones is independent of the PPAR-gamma receptor. Clin Endocrinol (Oxf). 2006;65:389–395
  45. Takeda M, Otsuka F, Otani H, Inagaki K, Miyoshi T, Suzuki J, et al. Effects of peroxisome proliferator-activated receptor activation on gonadotropin transcription and cell mitosis induced by bone morphogenetic proteins in mouse gonadotrope LbetaT2 cells. J Endocrinol. 2007;194:87–99
  46. Xu HE, Stanley TB, Montana VG, Lambert MH, Shearer BG, Cobb JE, et al. Structural basis for antagonist-mediated recruitment of nuclear co-repressors by PPARalpha. Nature. 2002;415:813–817
  47. Lee G, Elwood F, McNally J, Weiszmann J, Lindstrom M, Amaral K, et al. T0070907, a selective ligand for peroxisome proliferator-activated receptor gamma, functions as an antagonist of biochemical and cellular activities. J Biol Chem. 2002;277:19649–19657

PII: S0093-691X(09)00434-8

doi: 10.1016/j.theriogenology.2009.09.020

Theriogenology
Volume 73, Issue 3 , Pages 367-382 , February 2010

Article Tools

* Image Usage & Resolution