Theriogenology
Volume 73, Issue 3 , Pages 343-357 , February 2010

Venous blood lactate evaluation in equine neonatal intensive care

Received 31 October 2008 ,Revised 17 September 2009 ,Accepted 27 September 2009.

References 

  1. De Backer D. Lactic acidosis. Intensive Care Med. 2003;29:699–702
  2. Vary TC, Siegel JH, Nakatani T, Sato T, Aoyama H. Effect of sepsis on activity of pyruvate dehydrogenase complex in skeletal muscle and liver. Am J Physiol. 1986;250:634–640
  3. Chrusch C, Bands C, Bose D, Li X, Jacobs H, Duke K, et al. Impaired hepatic extraction and increased splanchnic production contribute to lactic acidosis in canine sepsis. Am J Respir Crit Care Med. 2000;161:517–526
  4. Bellomo R, Kellum JA, Pinsky MR. Transvisceral lactate fluxes during early endotoxemia. Chest. 1996;110:198–204
  5. Haji-Michael PG, Ladriere L, Sener A, Vincent JL, Malaisse WS. Leucocyte glycolysis and lactate output in animal sepsis and ex vivo human blood. Metabolism. 1999;48:779–785
  6. James JH, Luchette FA, McCarter FD, Fischer JE. Lactate is an unreliable indicator of tissue hypoxia in injury or sepsis. Lancet. 1999;354:505–508
  7. McCarter FD, James JH, Luchette FA, Wang L, Friend LA, King JK, et al. Adrenergic blockade reduces skeletal muscle glycolysis and Na+, K+-ATPase activity during hemorrhage. J Surg Res. 2001;99:235–244
  8. Levy B, Gibot S, Franck P, Cravoisy A, Bollaert PE. Relation between muscle Na+, K+-ATPase activity and raised lactate concentrations in septic shock: a prospective study. Lancet. 2005;365:871–875
  9. Levraut J, Ichai C, Petit I, Ciebiera JP, Perus O, Grimaud D. Low exogenous lactate clearence as an early predictor of mortality in normolactatemic critically ill septic patients. Crit Care Med. 2003;31:705–710
  10. Bakker J, Coffernils M, Leon M, Gris P, Vincent JL. Blood lactate levels are superior to oxygen-derived variables in predicting outcome in human septic shock. Chest. 1991;99:956–962
  11. Abramson D, Scalea TM, Hitchcock R, Trooskin SZ, Henry SM, Greenspan J. Lactate clearance and survival following injury. J Trauma. 1993;35:584–588
  12. Bakker J, Gris P, Coffernils M. Serial blood lactate levels can predict the development of multiple organ failure following septic shock. Am J Surg. 1996;171:221–226
  13. Duke TD, Butt W, South M. Predictors of mortality and multiple organ failure in children with sepsis. Intensive Care Med. 1997;23:684–692
  14. Hatherill M, Waggie Z, Purves L, Reynolds L, Argent A. Mortality and the nature of metabolic acidosis in children with shock. Intensive Care Med. 2000;29:286–291
  15. Backer DD, Creuter J, Silva E, Vincent JL. The hepatosplanchnic area is not a common source of lactate in patients with severe sepsis. Crit Care Med. 2001;29:256–261
  16. Kobayashi S, Gando S, Morimoto Y, Nanzaki S, Kemmotsu O. Serial measurement of arterial lactate concentration as a prognostic indicator in relation to the incidence of disseminated intravascular coagulation in patients with systemic inflammatory response syndrome. Surg Today. 2001;31:853–859
  17. Husain FA, Martin MJ, Mullenix PS, Steele SR, Elliott DC. Serum lactate and base deficit as predictors of mortality and morbidity. Am J Surg. 2003;185:485–491
  18. Cerović O, Golubović V, Spec-Man A, Kremzar B, Vidmar G. Relationship between injury severity and lactate levels in severely injured patients. Intensive Care Med. 2003;29:1300–1305
  19. Shapiro NI, Howell MD, Talmor D, Nathanson LA, Lisbon A, Wolfe RE, et al. Serum lactate as a predictor of mortality in emergency department patients with infections. Ann Emerg Med. 2005;45:524–528
  20. Trzeciak S, Dellinger RP, Chansky ME, Arnold RC, Schorr C, Milcarek B, et al. Serum lactate as a predictor of mortality in patients with infection. Intensive Care Med. 2007;33:970–977
  21. Moore JN, Owen R, Lumsden JH. Clinical evaluation of blood lactate levels in equine colic. Equine Vet J. 1976;8:49–54
  22. Parry B, Anderson GA, Gay CC. Prognosis in equine colic: a study of individual variables used in case assesment. Equine Vet J. 1983;15:337–344
  23. Orsini JA, Elser AH, Galligan DT. Prognostic index for acute abdominal crisis (colic) in horses. Am J Vet Res. 1988;49:1969–1971
  24. Furr MO, Lessard P, White NA. Development of a colic severity score for predicting the outcome of equine colic. Vet Surg. 1995;24:97–101
  25. Moore JN, Traver DS, Turner MF, White FJ, Huesgen JG, Butera TS. Lactic acid concentration in peritoneal fluid of normal and diseased horses. Res Vet Sci. 1977;23:117–118
  26. Genn HJ, Hertsch B. Diagnostical and prognostical value of blood lactate concentration and its level in peritoneal fluid in colic of the horse. Dtsch Tierarztl Wochenschr. 1982;6:295–299
  27. Latson KM, Nieto JE, Beldomenico PM, Snyder JR. Evaluation of peritoneal fluid lactate as a marker of intestinal ischaemia in equine colic. Equine Vet J. 2005;37:342–346
  28. Delesalle C, Dewulf J, Lefebvre RA, Schuurkes JAJ, Proot J, Lefere L, et al. Determination of lactate concentrations in blood plasma and peritoneal fluid in horses with colic by an Accusport analyzer. J Vet Int Med. 2007;21:293–301
  29. Brumbaugh GW, Benson PA. Partial pressure of oxigen and carbon dioxide, pH, and concentration of bicarbonate, lactate, and glucose in pleural fluid from horses. Am J Vet Res. 1990;51:1032–1037
  30. Tulamo RM, Bramlage LR, Gabel AA. The influence of corticosteroids on sequential clinical and synovial fluid parameters in joints with acute infectious arthritis in the horse. Equine Vet J. 1989;21:332–337
  31. Fielding CL, Magdesian KG. How to use venous blood lactate concentration to guide fluid therapy in adult horses. AAEP Proc. 2005;51:260–262
  32. Magdesian GK. Blood lactate levels in neonatal foals: normal values and temporal effects in the post-partum period. J Vet Emerg Crit Care. 2003;13:174
  33. Wotman K, Palmer JE, Boston RC, Wilkins PA. Lactate concentration in foals presenting to a neonatal intensive care unit: association with outcome. J Vet Intern Med. 2005;19:409
  34. Corley KTT, Donaldson LL, Furr MO. Arterial lactate concentration, hospital survival, sepsis and SIRS in critically ill neonatal foals. Equine Vet J. 2005;37:53–59
  35. Henderson ISF, Franklin RP, Wilkins PA, Boston RC. Association of hyperlactatemia with age, diagnosis, and survival in equine neonates. J Vet Emerg Crit Care. 2008;18:496–502
  36. Fell JW, Rayfield JM, Gulbin JP, Gaffney PT. Evaluation of the Accusport lactate analyzer. Int J Sports Med. 1998;19:199–204
  37. Pyne DB, Boston T, Martin DT, Logan A. Evaluation of the Lactate Pro blood lactate analyzer. Eur J Appl Physiol. 2000;82:112–116
  38. Evans DL, Golland LC. Accuracy of Accusport for measurement of lactate concentrations in equine blood and plasma. Equine Vet J. 1996;28:398–402
  39. Lindner A. Measurement of plasma lactate concentration with Accusport. Equine Vet J. 1996;28:403–405
  40. Simmons DB, Stewart AW, Stewart C, Pedler P, Roberts P. A comparative evaluation of the Accusport vs. conventional assay methods for the determination of lactate in equine plasma. J Equine Vet Sci. 1999;19:402–407
  41. Delasalle C, Dewulf J, Lefebvre RA, Schuurkes JAJ, Proot J, Lefere L, et al. Determination of lactate concentrations in blood plasma and peritoneal fluid in horses with colic by an Accusport analyzer. J Vet Int Med. 2007;21:293–301
  42. Silverman SC, Birks EK. Evaluation of the i-STAT hand held chemical analyzer during treadmill and endurance exercise. Equine Vet J Suppl. 2002;34:551–554
  43. Saulez MN, Cebra CK, Dailey M. Comparative biochemical analyses of venous blood and peritoneal fluid from horses with colic using a portable analyzer and an in-house analyzer. Vet Rec. 2005;157:217–233
  44. Tennent-Brown BS, Wilkins PA, Lindborg S, Russell G, Boston RC. Assessment of a point-of-care lactate monitor in emergency admissions of adult horses to a referral hospital. J Vet Intern Med. 2007;21:1090–1098
  45. Lindner A. Use of blood biochemistry for positive performance diagnosis of sport horses in practice. Revue Mèd Vèt. 2000;151:611–618
  46. Ferasin L, Dodkin SJ, Amodio A, Murrau JK, Papasouliotis K. Evaluation of a portable lactate analyzer (Lactate Scout) in dogs. Vet Clin Pathol. 2007;36:36–39
  47. Vaala WE. Perinatology. In:  Higgins AJ,  Snyder JR editor. The Equine Manual. 2nd edition. W.B. Saunders; 2006;p. 803–804
  48. Koterba AM. Diagnosis and management of the normal and abnormal neonatal foals: general considerations. In:  Koterba AM,  Drummond WH,  Kosch PC editor. Equine Clinical Neonatology. Lea & Febiger; 1990;p. 3–16
  49. Giguère S, Knowles HAJ, Valverde A, Bucki E, Young L. Accuracy of indirect measurement of blood pressure in neonatal foals. J Vet Int Med. 2005;19:571–576
  50. LeBlanc M. Immunologic consideration. In:  Koterba AM,  Drummond WH,  Kosch PC editor. Equine Clinical Neonatology. Lea & Febiger; 1990;p. 275–294
  51. Brewer BD, Koterba AM. The development of a scoring system for the early diagnosis of equine neonatal sepsis. Equine Vet J. 1988;20:18–22
  52. Corley KTT. Monitoring and treating haemodynamic disturbances in critically ill neonatal foals. Part 2: assessment and treatment. Equine Vet Educ. 2002;14:328–336
  53. Levy MM, Fink MP, Marshall JC, Abraham E, Angus D, Cook D, et al., for the International Sepsis Definitions Conference. 2001 SCCM/ESICM/ACCP/ATS/SIS International Sepsis Definitions Conference. Intensive Care Med 2003; 29:530-538.
  54. Harvey JW. Normal hematologic values. In:  Koterba AM,  Drummond WH,  Kosch PC editor. Equine Clinical Neonatology. Lea & Febiger; 1990;p. 561–570
  55. Bauer JE. Normal blood chemistry. In:  Koterba AM,  Drummond WH,  Kosch PC editor. Equine Clinical Neonatology. Lea & Febiger; 1990;p. 603–614
  56. Knottenbelt DC, Holdstock N, Madigan JE. Equine Neonatology Medicine and Surgery. Saunders; 2004;pp. 155-363
  57. Goldstein B, Giroir B, Randolph A and the Members of the International Consensus Conference on Pediatric Sepsis. International Pediatric Sepsis Consensus Conference: definitions for sepsis and organ dysfunction in pediatrics. Pediatr Crit Care Med. 2005;6:2–8
  58. Bland JM, Altman DG. Statistical methods for assessing agreement between two methods of clinical measurement. Lancet. 1986;8:307–310
  59. Acierno MJ, Meghan EJ, Eddleman LA, Mitchell MA. Measuring statistical agreement between four point of care (POC) lactate meters and a laboratory blood analyzer in cats. J Feline Med Surg. 2008;10:110–114
  60. Acierno MJ, Mitchell MA. Evaluation of four point of care meters for rapid determinations of blood lactate concentrations in dogs. J Am Vet Med Assoc. 2007;230:1315–1318
  61. Gambke B, Berg A, Fabian K, Francaux M, Haber P, Hartmann U, et al. Multicenter evaluation of portable system for determining blood lactate. J Lab Med. 1997;21:250–256
  62. Kitchen H, Rossdale PD. Metabolic profiles of newborn foals. J Reprod Fert. 1975;23:705–707
  63. Silver M, Ousey JC, Dudan FE. Studies on equine prematurity 2: post natal adrenocortical activity in relation to plasma adrenocorticotrophic hormone and catecholamine levels in term and premature foals. Equine Vet J. 1984;16:278–286
  64. Corley KTT. Monitoring and treating haemodynamic disturbances in critically ill neonatal foals. Part 1: haemodynamic monitoring. Equine Vet Educ. 2002;14:270–279
  65. Castagnetti C. Mariella J, Pirrone A, Iacono E, Mari G. Lactate concentration in amniotic fluid and in mare and foal blood at delivery. Hippos 2007 Proc; 173.
  66. Rossdale PD, Ousey JC, Silver M. Studies on equine prematurity 6: guidelines for assessment of fetal maturity. Equine Vet J. 1984;16:300–302
  67. Fowden AL, Taylor PM, White KL, Forhead AJ. Ontogenic and nutritionally induced changes in fetal metabolism in the horse. J Physiol. 2000;528:209–219
  68. Sparks JW, Hay WW, Bonds D, Meschia G, Battaglia FC. Simultaneous measurements of lactate turnover rate and umbilical lactate uptake in the fetal lamb. J Clin Invest. 1982;70:179–192
  69. Nordstrom L, Marcus C, Persson B, Shimojo N, Westgren M. Lactate in cord blood and its relationship to pH and catecholamines in spontaneous vaginal delivery. Early Hum Dev. 1996;46:97–104
  70. Westgren M, Divon M, Horal M, Ingemarsson I, Kublickas M, Shimojo N, et al. Routine measurements of umbilical artery lactate levels in the prediction of perinatal outcome. Am J Obstet Gynecol. 1995;173:1416–1422
  71. Gayle JM, Cohen N, Chaffin MK. Factors associated with survival in septicemic foals: 65 cases (1988-1995). J Vet Intern Med. 1998;12:140–146
  72. Corley KTT, Pearce G, Magdesian KG, Wilson WD. Bacteraemia in neonatal foals: clinicopathological differences between Gram-positive and Gram-negative infections, and single organism and mixed infections. Equine Vet J. 2007;39:84–89
  73. Hollis AR, Wilkins PA, Palmer JE, Boston RC. Bacteremia in equine neonatal diarrhea: a retrospective study (1990-2007). J Vet Intern Med. 2008;22:1203–1209
  74. Corley KTT. Monitoring and treating haemodynamic disturbances in critically ill neonate foal. Part II: assessment and treatment. Equine Vet Educ. 2002;14:328–336
  75. Corley KTT, Axon JE. Resuscitation and emergency management for neonatal foals. Vet Clin North Am Equine Pract. 2005;21:431–455
  76. Corley KTT. Monitoring and treating haemodynamic disturbances in critically ill neonate foal. Part I: haemodynamic monitoring. Equine Vet Educ. 2002;14:270–279
  77. Naylor JM. Severe metabolic acidemia, hypoglycemia, and sepsis in a 3-week-old Quarter Horse foal. Vet Clin Equine. 2006;22:95–106
  78. Zhang A, Altura BT, Altura BM. Elevation of extracellular magnesium rapidly raises intracellular free Mg2+in human aortic endothelial cells: is extracellular Mg2+ a regulatory cation?. Front Biosci. 1997;2:13–17

PII: S0093-691X(09)00432-4

doi: 10.1016/j.theriogenology.2009.09.018

Theriogenology
Volume 73, Issue 3 , Pages 343-357 , February 2010