Theriogenology
Volume 69, Issue 9 , Pages 1056-1060 , June 2008

Mid-gestation pregnancy termination in rabbits by the progesterone antagonist aglepristone

  • G.R. Özalp

      Affiliations

    • Department of Obstetrics and Gynecology, Faculty of Veterinary Medicine, Uludag University, Mudanya Cad. No. 2 Osmangazi, 16190 Bursa, Turkey
    • Corresponding Author InformationCorresponding author. Tel.: +90 224 234 76 55/128; fax: +90 224 234 63 95.
    • ,
  • K. Seyrek-İntaş

      Affiliations

    • Department of Obstetrics and Gynecology, Faculty of Veterinary Medicine, Uludag University, Mudanya Cad. No. 2 Osmangazi, 16190 Bursa, Turkey
    • ,
  • Ç. Çalışkan

      Affiliations

    • Department of Obstetrics and Gynecology, Faculty of Veterinary Medicine, Uludag University, Mudanya Cad. No. 2 Osmangazi, 16190 Bursa, Turkey
    • ,
  • A. Wehrend

      Affiliations

    • Clinic for Obstetrics, Gynecology and Andrology of Large and Small Animals, Justus-Liebig-University Giessen, Frankfurter Straße 106, D-35392, Germany

Received 19 June 2007 ,Revised 24 January 2008 ,Accepted 24 January 2008.

References 

  1. Hoffmann B, Schuler G. Receptor blockers—general aspects with respect to their use in domestic animal reproduction. Anim Reprod Sci. 2000;60/61:295–312
  2. Fieni F, Tainturier D, Bruyas JF, Bdinand F, Berthelot X, Ronsin P, et al. Etude clinique d’une anti-hormone pour provoquer l’avortement chez la chienne. Recueil de Médecine Vétérinaire. 1996;172:359–367
  3. Hubler M, Arnold S. Prevention of pregnancy in bitches with the progesterone antagonist aglepristone (alizine). Schweizer Archiv für Tierheilkunde. 2000;142:381–386
  4. Fieni F, Martal J, Marnet PG, Siliart B, Guittot F. Clinical, biological and hormonal study of mid-pregnancy termination in cats with aglepristone. Theriogenology. 2006;66:1721–1728
  5. Fieni F, Martal J, Marnet PG, Siliart B, Bernarnd F, Riou M, et al. Hormonal variation in bitches after early or mid-pregnancy termination with aglepristone (RU534). J Reprod Fertil Suppl. 2001;57:243–248
  6. Galac S, Kooistra HS, Butinar J, Bevers MM, Dieleman SJ, Voorhout G, et al. Termination of mid-gestation pregnancy in bitches with aglepristone, a progesterone receptor antagonist. Theriogenology. 2000;53:941–950
  7. Georgiev P, Wehrend A. Mid-gestation pregnancy termination by the progesterone receptor blocker aglepristone in queens. Theriogenology. 2006;65:1401–1406
  8. Georgiev P, Wehrend A, Penchev G, Vodenicharov A, Kauffold J, Leiser R. Histological changes of the feline cervix, endometrium and placenta after mid-gestational termination of pregnancy with aglepristone. Reprod Domes Anim; in press.
  9. Steiger K, Politt E, Hoeftmann T, Meyer-Lindenberg A, Schoon HA, Guenzel-Apel AR. Morphology of canine placental sites after induced embryonic or fetal death. Theriogenology. 2006;66:1709–1714
  10. Chang CC, Wang WC, Bardin CW. Termination of early pregnancy in the rat, rabbit, and hamster with RU 486 and anordrin. Contraception. 1993;47:597–608
  11. Saksena SK, Chang MC, Lau IF. Termination of pregnancy in rabbit and mouse by Trichosanthin. Contraception. 1979;20:367–376
  12. Corrada Y, Garćia P, de la Sota PE, Huzman M, Landoni MF, Gobello C. Decrease of body temperature after aglepristone treatment in bitches. Anim Reprod Sci. 2005;87295–87299
  13. Easson W. A review of rabbit and rodent production medicine. Semin Avian Exot Pet Med. 2001;10:131–139
  14. Wehrend A, Georgiev P. Experience with the use of the progesterone antagonist aglepristone in bitches and queens. Tierärztliche Praxis. 2006;34:409–414
  15. Philibert D. RU 46534 Affinité relative de liaison pour les récepteurs stéroidiens- activité antiprogestérone in vivo. Rapport d’étude interne Roussel Uclaf. 1994;

PII: S0093-691X(08)00060-5

doi: 10.1016/j.theriogenology.2008.01.016

Theriogenology
Volume 69, Issue 9 , Pages 1056-1060 , June 2008

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