Theriogenology
Volume 61, Issue 6 , Pages 1085-1099 , 15 April 2004

Effect of bovine viral diarrhea virus infection on fertility of dairy heifers

  • Claudia A. Muñoz-Zanzi

      Affiliations

    • Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, CA 95616, USA
    • Corresponding Author InformationCorresponding author. Present address: Department of Clinical and Population Sciences, College of Veterinary Medicine, University of Minnesota, 1365 Gortner Ave. St. Paul, MN 55108, USA. Tel.: +1-612-625-7755; fax: +1-612-625-6241.
    • ,
  • Mark C. Thurmond

      Affiliations

    • Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, CA 95616, USA
    • ,
  • Sharon K. Hietala

      Affiliations

    • California Animal Health and Food Safety Laboratory, University of California, Davis, CA 95616, USA

Received 26 February 2003 ,Accepted 2 June 2003.

References 

  1. Houe H. Epidemiological features and economical importance of bovine virus diarrhea virus (BVDV) infections. Vet. Microbiol. 1999;64:89–107
  2. Roeder P, Drew R. Mucosal disease of cattle: a late sequel to fetal infection. Vet. Rec. 1984;114:309–313
  3. Roeder P, Jeffrey M, Cranwell M. Pestivirus fetopathogenicity in cattle: changing sequelae with fetal maturation. Vet. Rec. 1986;118:44–48
  4. Ross C, Dubovi E, Donis R. Herd problem abortions and malformed calves attributed to bovine viral diarrhea. J. Am. Vet. Med. Assoc. 1986;188:618–619
  5. Virakul P, Fahning M, Soo H, Zemjanis R. Fertility of cows challenged with a cytopathic strain of bovine viral diarrhea virus during an outbreak of spontaneous infection with a noncytophatic strain. Theriogenology. 1988;29:441–449
  6. Pritchard G, Borland E, Wood L, Pritchard D. Severe disease in a dairy herd associated with acute infection with bovine virus diarrhea virus, Leptospira hardjo and Coxiella burnetti. Vet. Rec. 1989;124:625–629
  7. McGowan M, Kirkland P, Littlejohns I. Increased reproductive losses in cattle infected with bovine pestivirus around the time of insemination. Vet. Rec. 1993;133:39–43
  8. David G, Crawshaw T, Gunning R, hibberd R, Lloyd G, Marsh P. Severe disease in adult dairy cattle in three UK dairy herds associated with BVD virus infection. Vet. Rec. 1994;134:468–472
  9. Larsson B, Niskanen R, Alenius S. Natural infection with bovine viral diarrhea virus in a dairy herd: a spectrum of symptoms including early reproductive failure and retained placenta. Anim. Reprod. Sci. 1994;36:37–48
  10. McGowan M, Kirkland P. Early reproductive loss due to bovine pestivirus infection. Br. Vet. J. 1995;151:263–270
  11. Woodard L. BVD virus associated with outbreaks of abortion, stillbirths, and weak calves. Vet Med 1994;April:379–84.
  12. Carman S, van Dreumel T, Ridpath J, Hazlett M, Alves D, Dubovi E, et al.  Severe acute bovine viral diarrhea in Ontario, 1993–1995. J. Vet. Diagn Invest. 1998;10:27–35
  13. Grahn T, Fahning M, Zemjanis R. Nature of early reproductive failure caused by bovine viral diarrhea virus. J. Am. Vet. Med. Assoc. 1984;185:429–433
  14. Whitmore H, Zenjamis R, Olson J. Effect of bovine viral diarrhea virus on conception in cattle. J. Am. Vet. Med. Assoc. 1981;178:1065–1067
  15. Meyling A, Jensen A. Transmission of bovine virus diarrhea virus (BVDV) by artificial insemination (AI) with semen from a persistently-infected bull. Vet. Microbiol. 1988;17:97–105
  16. Kirkland P, McGowan M, Mackintosh S, Moyle A. Insemination of cattle with semen from a bull transiently infected with pestivirus. Vet. Rec. 1997;140:124–127
  17. Michel P, Thurmond M, Hietala S. Prevaccination bovine viral diarrhea virus titers and subsequent reproductive performance in dairy heifers. Can J. Vet. Res. 1993;57:236–240
  18. Rufenacht J, Schaller P, Audige L, Knutti B, Kupfer U, Peterhans E. The effect of infection with bovine viral diarrhea virus on the fertility of Swiss dairy cattle. Theriogenology. 2001;56:199–210
  19. Thurmond M, Picanso J, Hietala S. Prospective serology analysis in diagnosis of dairy cow abortion. J. Vet. Diagn Invest. 1990;2:274–282
  20. Valle P, Martin S, Skjerve E. Time-to-first calving and calving interval in bovine virus diarrhoea virus (BVDV) sero-converted dairy herds in Norway. Prev. Vet. Med. 2001;51:17–36
  21. Rush D, Thurmond M, Muñoz-Zanzi C, Hietala S. Descriptive epidemiology of the risk of bovine viral diarrhea virus infection in intensively managed dairy replacement heifers. J. Am. Vet. Med. Assoc. 2001;219:1426–1431
  22. Evermann J, Ridpath J. Clinical and epidemiological observations of bovine viral diarrhea virus in the northwestern United States. Vet. Microbiol. 2002;89:129–139
  23. Ssentongo Y, Johnson R, Smith J. Association of bovine viral diarrhoea-mucosal disease virus with ovaritis in cattle. Aust. Vet. J. 1980;56:272–275
  24. Grooms D, Brock K, Pate J, Day M. Changes in ovarian follicles following acute infection with bovine viral diarrhea virus. Theriogenology. 1998;49:595–605
  25. Muñoz-Zanzi C, Thurmond M, Johnson W, Hietala S. Predicted ages of dairy calves when colostrum-derived bovine viral diarrhea virus antibodies would no longer offer protection against disease or interfere with vaccination. J. Am. Vet. Med. Assoc. 2002;221:678–685
  26. Muñoz-Zanzi C, Hietala S, Thurmond M, Johnson W. Quantification, risk factors, and health impact of natural congenital infection with bovine viral diarrhea virus in dairy calves. Am. J. Vet. Res. 2003;64:358–365
  27. National Research Council. Subcommittee on standardized methods for veterinary microbiology. In: George E Cottral, editor. Manual of standardized methods in veterinary microbiology. New York: Comstock Pub. Associates; 1978.
  28. Pare J, Hietala S, Thurmond M. An enzyme-linked immunosorbent assay (ELISA) for serological diagnosis of Neospora sp. infection in cattle. J. Vet. Diagn Invest. 1995;7:352–359
  29. Cole J, Ellinghausen H, Rubin H. Laboratory diagnosis of leptospirosis of domestic animals. US Anim Health Assoc 1979;189–99.
  30. Guitian J, Thurmond M, Hietala S. Infertility and abortion among first-lactation dairy cows seropositive or seronegative for Leptospira interrogans serovar hardjo. J. Am. Vet. Med. Assoc. 1999;215:515–518
  31. Ridpath JF, Bolin SR. Differentiation of types 1a, 1b, and 2 bovine viral diarrhea virus (BVDV) by PCR. Mol. Cell Probes. 1998;12:101–106
  32. Thurmond M, Muñoz-Zanzi C, Hietala S. Effect of calfhood vaccination on bovine viral diarrhea virus (BVDV) transmission under typical drylot dairy conditions and exposures. J. Am. Vet. Med. Assoc. 2001;219:968–975
  33. Jones L, Van Campen H, Xu Z-C, Schnackel J. Comparison of neutralizing antibodies to type 1a, 1b, and 2 bovine viral diarrhea virus from experimentally infected and vaccinated cattle. Bovine Practitioner. 2001;35:137–140
  34. Nagai M, Ito T, Sugita S, Genno A, Takeuchi K, Ozawa T, et al.  Genomic and serological diversity of bovine viral diarrhea virus in Japan. Arch. Virol. 2001;146:685–696
  35. Collet D. Modelling survival data. In: Chatfield C, Zidek JV, editors. Modelling survival data in medical research. London: Chapman & Hall; 1994. p. 53–61.
  36. Therneau T, Grambsch P. Testing proportional hazards. In: Dietz K, Gail M, Krickeberg K, Tsiatis A, Samet J, editors. Modeling survival data. Extending the Cox model. New York: Springer; 2000. p. 127–48.
  37. Martin S, Meek A, Willeberg P. Disease causation. In: veterinary epidemiology. Principles and methods. Ames, IA: Iowa State University Press; 1987. p. 130–1.
  38. Collet D. Modelling binary data. In: Chatfield C, Zidek JV, editors. London: Chapman & Hall; 1991.
  39. Grooms D, Brock K, Ward L. Detection of cytopathic viral diarrhea virus in the ovaries of cattle following immunization with a modified live bovine viral diarrhea virus vaccine. J. Vet. Diagn Invest. 1998;10:130–134
  40. Grooms D, Brock K, Ward L. Detection of bovine viral diarrhea virus in the ovaries of cattle acutely infected with bovine viral diarrhea virus. J. Vet. Diagn Invest. 1998;10:125–129
  41. McGowan M, Kafi M, Kirkland P, Kelly R, Bielefeldt Ohmann H, Occhio M, et al.  Studies of the pathogenesis of bovine pestivirus-induced ovarian dysfunction in superovulated dairy cattle. Theriogenology. 2003;59:1051–1066
  42. Larsson B, Traven M, Hulten C, Hard A, Segerstad C, Blelak K, et al.  Serum concentrations of thyroid hormones in calves with a transient or persistent infection with bovine viral diarrhea virus. Res. Vet. Sci. 1995;85:186–189
  43. Fray M, Mann G, Clarke M, Charleston B. Bovine viral diarrhea virus: its effects on estradiol, progesterone, and prostaglandin secretion in the cow. Theriogenology. 1999;51:1533–1546
  44. Fray M, Mann G, Clarke M, Charleston B. Bovine viral diarrhea virus: its effects on ovarian function in the cow. Vet. Microbiol. 2000;77:185–194
  45. Youngquist R. Bovine theriogenology. In: Current therapy in large animal theriogenology. Philadelphia: Saunders; 1997. p. 898.
  46. Hamers C, Di Valentin E, Lecomte C, Lambot M, Joris E, Genicot B, et al.  Virus neutralizing antibodies against a panel of 18 BVDV isolates in calves vaccinated with Rispoval RS-BVD. J. Vet. Med. B. 2000;47:721–726
  47. Fulton R, Burge L. Bovine viral diarrhea virus types 1 and 2 antibody response in calves receiving modified live virus or inactivated vaccines. Vaccine. 2001;19:264–274
  48. Ellis W. Leptospirosis as a cause of reproductive failure. Vet. Clin. North Am.: Food Anim. Pract. 1994;10:463–478
  49. Heath S, Johnson R. Leptospirosis. J. Am. Vet. Med. Assoc. 1994;205:1518–1523
  50. Waldner C, Henderson J, Wu J, Breker K, Chow E. Reproductive performance of a cow-calf herd following a Neospora caninum-associated abortion epidemic. Can. Vet. J. 2001;42:355–360

PII: S0093-691X(03)00295-4

doi: 10.1016/j.theriogenology.2003.06.003

Theriogenology
Volume 61, Issue 6 , Pages 1085-1099 , 15 April 2004

Article Tools

* Image Usage & Resolution